Found 32 matching trials
Safety, Tolerability and Efficacy of PfSPZ Vaccine Against Heterologous CHMI in US Malaria naïve Adults PHASE1 This is a randomized, double blind, placebo-controlled, single site, trial ...
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Fred Hutchinson Cancer Research Center
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Safety and Immunogenicity in Age De-Escalation of PfSPZ Vaccine in Tanzanian Adults, Children, and Infants PHASE1 The present trial will evaluate safety and tolerability as well as the vacc...
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Bagamoyo Research and Training center of the Ifakara Health Institute
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Safety and Preliminary Efficacy of the Malaria Vaccine Candidates Falciparum Merozoite Protein-1 (FMP1) and SmithKlineBeecham (SKBB) Candidate Malaria Vaccine RTS,S PHASE1 The purpose of this study is to see if two new malaria vaccines called FMP1...
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WRAIR Clinical Trials Center
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PfSPZ Challenge in Healthy Malaria-Naïve Adults in the United States PHASE1 This phase I trial of the replication-intact PfSPZ Challenge vaccine given ...
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Kaiser Permanente Washington Health Research Institute - Vaccines and Infectious Diseases
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Trial for Malaria Vaccine Candidate, PfPEBS (P. Falciparum Pre-Erythrocytic and Blood Stage) PHASE1 This study intends to test the hypothesis that the malaria antigen PfPEBS, ...
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Centre Hospitalier Universitaire Vaudois (CHUV)
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Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falcipa... PHASE1 Background:
Malaria remains a major global health problem. Malaria is spre...
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Malaria Vaccine Center STTB/MRTC
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Regimen Optimization Trial of PfSPZ Vaccine in Equatorial Guinea PHASE1 This is a phase 1, randomized regimen optimization study of PfSPZ Vaccine i...
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Baney Clinical Research Center
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Trial to Evaluate the Safety, Immunogenicity and Protective Efficacy of Three or Five Administrations of GAP3KO Sporozoites PHASE1 This Phase 1 trial will include 16 subjects who will receive the Geneticall...
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Kaiser Permanente Washington Health Research Institute
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Trial to Evaluate L9LS in Healthy Adults PHASE1 Background:
Malaria is a parasitic disease carried by mosquitoes in tropic...
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National Institutes of Health Clinical Center
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Controlled Human Malarial Infection by Intravenous Injection of Plasmodium Falciparum Sporozoites in Non-Immune Adults PHASE1 The study is designed to establish the best dose to safely infect healthy i...
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Eberhard Karls University of Tübingen, Germany
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